The most effective treatment for methamphetamine use disorders can be made even better by rewarding patients for abstinence. In a 12-week study, Roll et al. (p. 1993) compared treatment as usual with and without escalating prizes for achievement of goals. The patients receiving prizes in addition to treatment as usual had significantly more stimulant-negative urine samples and longer intervals of abstinence. For most patients, usual treatment was Matrix model therapy, a combination of relapse prevention, family and group therapies, drug education, self-help, and drug abuse monitoring. Prize-based contingency management adds operant conditioning, which has previously proven to be helpful in treating cocaine and other substance use disorders. Dr. Stephen Higgins comments on behavioral treatment of methamphetamine abuse in an editorial on p. 1870.