Clinical Guidance: Psychiatric Risk Factors for Mild Cognitive Impairment in Older Adults
Agitation, apathy, anxiety, irritability, and depression in elderly persons are associated with greater risk for development of mild cognitive impairment, the intermediate stage between normal cognitive aging and dementia. As reported by Geda et al. (p. 572), 1,587 cognitively normal community-dwelling adults and their spouses or other informants were interviewed at age 70–90 and again 4–5 years later. Although nonpsychotic symptoms at baseline were related to mild cognitive impairment at follow-up, baseline delusions and hallucinations were not.