Psychopharmacology here is related to a dimensional view of psychopathology in the cancer patient using the Rapid Dimensional Assessment Scale: sadness/demoralization, anger/irritability, impulsiveness, activation, obsessionality, apathy, reality distortion, thought disorganization, somatic preoccupation, and somatization. The dimensional analysis overcomes distinctions among subthreshold major depression, mild major depression or adjustment disorder, generalized anxiety disorder comorbid with mood disorder, and mixed anxiety-depressive disorder. The best-fitting diagnostic criteria the authors find less interesting than the exploration of several dimensions and the severity, duration, and shape of the profile of suffering. By dimensions, they tailor antidepressants as antistress pills. Ongoing psychosocial intervention is the prerequisite of any psychotropic prescription.