Tremendous amounts of time, energy, and ink (perhaps less ink these days) have been expended in the pursuit of a more “human” approach to medical practice. Familiar names associated with this quest, such as Michael Balint and George Engel, are proudly claimed by psychoanalysis. However, with no direct connection to any mental health field, Eric Cassell may be the most influential living advocate for compassionate, well-rounded doctoring. Perhaps best known for the various iterations of his book The Nature of Suffering and the Goals of Medicine, Cassell’s work spans decades and has contributed to the education of generations of physicians. His latest book, The Nature of Healing: The Modern Practice of Medicine, has the feel of a summation of that work and also of its evolution and extension.