In this issue, we debut a new series, Treatment in Psychiatry, in which an author with well-recognized expertise provides a hypothetical case vignette that represents a commonly encountered issue in patient care, summarizes the relevant research literature, and then offers an opinion on how to proceed with assessment and treatment. Similar to the Clinical Practice series in The New England Journal of Medicine, this new series complements our existing Clinical Case Conferences, which present actual patients with disguised identities who posed especially difficult or unique problems in diagnosis or treatment. Case Conferences should reflect discussion of a case at a clinical or academic departmental meeting. Authors who wish to contribute to either series are encouraged to contact the editors at AJP@psych.org before preparing a paper. Single cases reports of unusual presentations of illness or reactions to treatment are welcome as Letters to the Editor.