This is a "how to" manual in the best tradition for those engaged in the ongoing care of patients suffering from the most common mental disorders encountered in clinical practice. It takes a practical approach, addressing every phase of drug management from the first encounter with a patient to treatment termination. Thus, every component of care is covered, including management of the "difficult" patient (e.g., the overly anxious, the poorly compliant, and the borderline personality). In this context, it also reflects on the clinician who may be overwhelmed by the workload of a busy practice, making the important point that such stress may be misinterpreted as the patient’s problem.