"Clinical Practice and the Biopsychosocial Approach" is an impressive chapter seamlessly written by six authors, nicely bringing Dr. Engel’s description of biopsychosocial understanding to an up-to-date approach to therapeutic practices. Subsequent chapters address other clinical applications, research, educational and administrative perspectives, and, finally, some historical background and some brief notes on comparisons with systems theory and current patient-centered and relationship-centered approaches to health care. The book is a pleasant and interesting read for those with an interest in this area, although it is written about nonpsychiatric primary care. It certainly would be relevant in training medical students and residents, as well as for use on consultation-liaison services. This volume provides a good background but is more of a well-rounded, thoughtful collection than an ideal textbook. For didactic purposes, selected chapters would do well, including Dr. Engel’s two reprinted papers.