One chapter discusses treating depressed alcohol-dependent individuals, and another tries to measure the utility of psychosocial interventions such as psychotherapy and Alcoholics Anonymous (AA) in treating substance-dependent patients with bipolar disorder. Researchers from the Netherlands screened 116 drug-abusing patients for anxiety and mood disorders and compared three means of doing so: a symptom checklist before detoxification, a symptom checklist after detoxification, and a structured interview. A group of Yale psychiatrists review the literature on the association of posttraumatic stress disorder with substance abuse. They cover phenomenology, epidemiology, and neurophysiology. They report promising developments in the pharmacological treatment of this population. One article reports a study of correlates of substance abuse in patients with schizophrenia, including intensity of symptoms, demographics, medication side effects, and social functioning. The final chapter reports on a prospective study of the value of personality assessment in predicting vulnerability to substance abuse, with a review of the pertinent literature.