The book is divided into four major sections. The first, Biological Bases of Pediatric Psychopharmacology, provides "a foundation of neurobiology upon which the rest of the volume is built." This section consists of three subsections—Developmental Principles of Neurobiology and Psychopharmacology, Genetic Principles, and Developmental Psychopathology. The second section, Somatic Interventions, reviews psychotropic agents used in pediatric psychopharmacology as well as other somatic treatments, such as complementary and alternative medicine approaches, ECT, and transcranial magnetic stimulation. The third section, Assessment and Treatment, begins with general principles such as clinical assessment, clinical instruments and scales, the psychology of prescribing, and combining pharmacotherapy and psychotherapy. It continues with a focus on treatment of specific disorders and syndromes and discussions of special clinical populations such as substance-abusing youth, individuals with mental retardation, medically ill children and adolescents, and preschoolers. The section closes with a focus on other areas of clinical concern such as aggression, agitation, and elimination disorders. The last section, Epidemiological, Research, and Methodological Considerations, reviews issues such as the methodology and design of clinical trials, regulatory issues, ethical issues in research, and international perspectives. An appendix titled Pediatric Psychopharmacology at a Glance provides a summary table of medications used in pediatric psychopharmacology.