We presented catatonia as a distinct syndrome that is identifiable by its psychopathology, occurs in a wide range of psychiatric disorders, and is responsive to defined interventions. We suggested that catatonia deserves a class of its own in psychiatric classifications, much as delirium and dementia are individually defined. We presented extensive evidence that catatonia is not limited to a subtype of schizophrenia (295.2) or secondary to a medical condition (293.89), as formulated in DSM-IV-TR.