This is a very comprehensive textbook of enormous value to all who deal with dementias. I have no reservations about the book whatsoever. However, the reader will find a plethora of information that is, at least for now, of heuristic merit without much in the way of active intervention. There is an epilogue by Elaine Murphy, M.D., Ph.D., F.R.C.Psych., which could have served as an excellent book review on its own. Having read this entire book in 1 week, she concludes that although there has been an explosion of knowledge and some reason for optimism, major advances still seem "just over the next mountain range." Chapter 4, "Assessment and Differential Diagnosis of Dementia," which essentially presents the workup a psychiatrist would do, does not differ substantially from what I learned in residency 40 years ago. What has changed is the therapeutic nihilism that used to be abroad. This book provides the reasons for optimism that eventually we will better understand the neurophysiology and pathophysiology of dementia.