This confused us because Dr. Levitan and colleagues did not assess endogenous or atypical depression subtypes. Instead, they examined the relation of trauma to three reverse versus typical neurovegetative symptoms: increased appetite, weight gain, and hypersomnia versus decreased appetite, weight loss, and insomnia. We assume they meant to equate reverse neurovegetative symptoms with atypicality and typical neurovegetative symptoms with endogeneity. However, the relation of stress to depression symptoms versus subtypes/syndromes should be distinguished. For example, these typical symptoms are just as likely to be present in subjects with nonendogenous/nonatypical depression as in endogenous depression. Nevertheless, the comments by Drs. Levitan and Parikh highlight a crucial test that remains to be undertaken comparing endogenous, atypical, and nonendogenous/nonatypical depressive subtypes. This may reveal further specificity.