To the Editor: Dr. Kelly’s letter makes an interesting point that we did not address in our article. There is a gradient of disorders related to schizophrenia (e.g., schizotypal personality disorder, quasi-psychotic conditions); each of these related disorders may, in part, have its origins in errors of fetal development. Each error of fetal development may be signaled by a specific set of minor physical anomalies. To a significant degree, the nature of the specific minor physical anomaly observed may be determined by the timing of disturbances during the process of gestation. This same timing of developmental disturbance may also help determine the nature of the neural developmental deficit and the associated behavioral disorder. Note that these conditions tend to result in the set of findings summarized by Dr. Kelly.