0
Get Alert
Please Wait... Processing your request... Please Wait.
You must sign in to sign-up for alerts.

Please confirm that your email address is correct, so you can successfully receive this alert.

1
Letter to the Editor   |    
Problems With Odds Ratios
WEN-HUNG KUO, Ph.D., Sc.M.
Am J Psychiatry 2003;160:191-191. doi:10.1176/appi.ajp.160.1.191

To the Editor: In the post hoc analysis section of his article, Dr. Bovasso identified the significant baseline covariates for the incidence of suicidal ideation. It is obvious that the risk set Dr. Bovasso used to calculate the incidence rate was the population that was free from a history of any of the nine depressive symptoms in the DSM-III depression module. However, the method for determining the risk set (denominator) of this analysis was not necessarily appropriate. Instead of excluding all of the Epidemiologic Catchment Area (ECA) participants with any baseline depressive symptoms from the post hoc analysis, only participants with a history of suicidal ideation should have been excluded. Under this definition, 1,708 ECA participants—instead of 849—would have been susceptible to the incidence of suicidal ideation. In an analysis by my colleagues and me (1), also of the Baltimore ECA sample, 89 participants reported new onset of suicidal ideation. Among all of the sociodemographic covariates, only age was significantly associated with the incidence of suicidal ideation (odds ratio=0.96, confidence interval [CI]=0.94–0.98; Wald χ2=16.2, df=1, p<0.001). Gender and race were not associated with suicidal ideation (1). However, our analysis did find that cannabis use at baseline was associated with the incidence of suicidal ideation; cannabis abusers were three times as likely to develop suicidal ideation as were nonabusers (odds ratio=3.00, CI=1.46–6.18; Wald χ2=8.9, df=1, p<0.01). Even after adjustment for the baseline diagnosis of any depressive episode, cannabis abuse remained a significant risk factor for new onset of suicidal ideation (odds ratio=3.14, CI=1.52–6.50; Wald χ2=9.6, df=1, p<0.01; data not published).

Kuo WH, Gallo JJ, Tien AY: Incidence of suicide ideation and attempts in adults: the 13-year follow-up of a community sample in Baltimore, Maryland. Psychol Med  2001; 31:1181-1191
[PubMed]
 
+

References

Kuo WH, Gallo JJ, Tien AY: Incidence of suicide ideation and attempts in adults: the 13-year follow-up of a community sample in Baltimore, Maryland. Psychol Med  2001; 31:1181-1191
[PubMed]
 
+
+

CME Activity

There is currently no quiz available for this resource. Please click here to go to the CME page to find another.
Submit a Comments
Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discertion of APA editorial staff.

* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe



Related Content
Books
The American Psychiatric Publishing Textbook of Geriatric Psychiatry, 4th Edition > Chapter 2.  >
DSM-5™ Clinical Cases > Chapter 2.  >
DSM-5™ Handbook of Differential Diagnosis > Chapter 2.  >
Dulcan's Textbook of Child and Adolescent Psychiatry > Chapter 56.  >
The American Psychiatric Publishing Textbook of Geriatric Psychiatry, 4th Edition > Chapter 8.  >
Topic Collections
Psychiatric News
APA Guidelines