Received July 26, 2000; revision received Jan. 29, 2001; accepted Feb. 12, 2001. From the Department of Psychiatry, Dalhousie University; the Department of Pediatrics, IWK-Grace Health Centre, Halifax, N.S., Canada; the Department of Psychiatry, University of Toronto, Toronto; and the Department of Psychiatry, University of British Columbia, Vancouver, B.C., Canada. Address reprint requests to Dr. Kopala, Department of Psychiatry, Dalhousie University, 9091, AJLB, 5909 Veterans’ Memorial Lane, Halifax, NS, Canada B3H 2E2; firstname.lastname@example.org (e-mail). Supported by the Stanley Foundation Scholars Program (Drs. Kopala, Honer, and Morrison), the Medical Research Council of Canada (Drs. Kopala, Bassett, and Honer), the Ontario Mental Health Foundation (Dr. Bassett), the Ian Douglas Bebensee Foundation (Dr. Bassett), the National Alliance for Research on Schizophrenia and Depression (Dr. Good), and the Department of Health, Province of Nova Scotia. The authors thank J. Hogan, M. Woschee, A. Feldstein, M. Brennan, L. Ford, and L. Maughan for their assistance.