The next chapter provides a comprehensive guide to diagnostic assessment. In addition to a practical guide to available instruments and techniques, there are also illuminating chapters on the extensive comorbidity of ADHD with other disorders such as unipolar and bipolar affective disorders, anxiety disorders, and substance abuse. There is a chapter on difficult diagnostic situations often confronted by clinicians working with adult patients, such as the patient with adult ADHD symptoms in whom the childhood syndrome cannot be elicited. The remaining chapters furnish a comprehensive guide to pharmacotherapy and psychosocial therapies for adults with ADHD and reviews of the effects of the disorder on school, work, and family functioning, the latter being particularly critical given the high likelihood that an identified patient will have parents, siblings, or children who also have ADHD. The climax of the book is a remarkable chapter in which each of the members of a family—mother and young son who have ADHD and father and daughter who do not—have written down their life stories in their own words, affording an intimate glimpse into the subjective experience of patients and their families.