Treatment is the book’s strongest suit, with 73 pages devoted to cognitive behavior therapy, 205 pages to medications and other somatic treatments, and 45 pages to combined treatments. Obviously, the meat of the matter is somatic therapy, and this is where I would go for comprehensive, in-depth reviews of standard as well as more creative interventions. Treatment resistance is dealt with in many of the chapters, and, fortunately, there is much of substance to be found. There is no question that among the anxiety disorders, OCD is the only one for which there is a substantial body of information on managing treatment-resistant or refractory patients. What I consider to be a rather glaring omission is the fact that there is no chapter on the treatment of child and adolescent OCD. This, in turn, may account for an absence of information on immune therapies such as plasmapheresis.