Overall, the book is very good. The topics are important, their organization is sensible, and the chapters are written clearly by productive researchers. Although some chapters are relatively brief, most are long enough to provide at least moderate levels of depth about their subjects. As in any complicated field, not all areas of research can be included, nor all conceptual models stressed. With that caveat, some important areas of research received less emphasis than might be expected. In both part 2 and part 3, for example, considerable emphasis was placed (correctly) on problems of attention or perception in schizophrenic illness. By contrast, much less emphasis was placed on long-term memory and executive functions, which are also well-documented areas of deficit. Moreover, other areas might have received additional emphasis. A lot of current thinking about the development of schizophrenia, for instance, involves neurodevelopmental models. This was certainly made explicit in the chapters by Cannon and by Walker et al. and was implicit in other chapters in part 1. It is a major theme with multiple alternative viewpoints that might have been considered in more detail. The same argument might be made about the degree of emphasis accorded to biological correlates of schizophrenia. In the epilogue, Richard R.J. Lewine stresses the "strong biological orientation" of the book. This may reflect one’s view of whether the glass is half full or half empty. Some types of biological factors are represented (e.g., in the etiological roles of genetic and environmental factors, in the neuronal model based on the nucleus accumbens, and in the neurodevelopmental theories that were stressed), but others are not. With the exception of a positron emission tomography study, there was little reference to the growing literature on structural and functional brain abnormalities in patients with schizophrenia and their biological relatives. Similarly, selected neurochemical abnormalities were discussed mainly in two out of 17 chapters.