The book will be most appreciated by health professionals and students, especially those in primary and emergency care settings. It is organized by drug type (e.g., sedatives, stimulants, inhalants, cannabinols), and each chapter contains brief sections on pharmacology, epidemiology, medical uses, the natural history of dependence, and making a diagnosis. Following this are sections on emergency problems involving the particular class of drugs, including their diagnosis and treatment. Alcohol and alcoholism receive the greatest emphasis, reflecting Schuckit’s interest and experience, but the other drugs are not short-changed. The author includes clinically relevant discussions of caffeine, nicotine, and over-the-counter and prescription drugs, including laxatives and anabolic steroids among many others. Additional chapters provide general overviews of addiction, rehabilitation, and prevention. Finally, there is a summary chapter on emergency problems related to substances: toxic reactions, withdrawal states, delirium and other cognitive disorders, psychosis, flashbacks, and anxiety/depressive states. For each problem category, the most common clinical pictures, differential diagnosis, and principles of treatment are clearly outlined.