Received March 1, 2000; revision received June 1, 2000; accepted June 7, 2000. From the Department of Psychiatry and Behavioral Sciences, Medical Branch, the University of Texas at Galveston; the Department of Psychiatry, Columbia University, and the New York State Psychiatric Institute, New York; the School of Medicine, Case Western Reserve University, Cleveland; the National Association for the Mentally Ill, Washington, D.C.; the Biological Psychiatry Program, Department of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati; the National Depressive and Manic-Depressive Association, Chicago; the NIMH, Bethesda, Md.; Massachusetts General Hospital, Harvard Medical School, Boston; and Rush-Presbyterian–St. Luke’s Medical Center, Chicago.Address reprint requests to Dr. Hirschfeld, Department of Psychiatry and Behavioral Sciences, Medical Branch, University of Texas at Galveston, 1.302 Rebecca Sealy, 301 University Blvd., Galveston, TX 77555-0188; email@example.com (e-mail). Supported by an unrestricted educational grant from Abbott Laboratories.The authors thank David M. Medearis, B.S., for assistance in the preparation of this article.