The two volumes reviewed here take very different approaches. TheAmerican Psychiatric Press Textbook of Neuropsychiatry seeks to be encyclopedic and offers in-depth reviews of basic neuroscience, clinical evaluation, structural and functional diseases of the brain, and general principles of treatment. Although there are useful chapters on schizophrenia by Carol Tamminga and mood disorders by Mayberg, Mahurin, and Brannan, the bulk of the chapters focus either on the evaluation of individuals with presumed neuropsychiatric disorder or on conditions such as headache, seizure disorder, sleep disorder, brain tumors, HIV infection, and Alzheimer’s disease. Neuropsychiatry and Mental Health Services, on the other hand, offers focused reviews of fewer topics. It, too, seeks to link current understanding of brain function and dysfunction to the treatment of conditions such as substance abuse, HIV infection, and developmental disabilities, but the chapters are much more clinical in nature and place less emphasis on presumed or plausible mechanisms of pathogenesis.