As with any multiauthored, single-issue monograph, there is a fair amount of repetition: 1) OCD is more prevalent than often supposed (about 1%–2% in the general population), 2) there is a purported neurological substrate (corticostriatal-thalamocortical), 3) there is a purported molecular basis (serotonin neurotransmission), 4) there is now effective pharmacological treatment (about 50% of patients have a fair response to selective serotonin reuptake inhibitors), 5) behavioral/psychosocial therapy is effective (about the same as pharmacological treatment), and 6) combined pharmacological and behavioral/psychosocial treatment has advantages (medication allows more people to engage in behavioral/psychosocial therapy and behavioral/psychosocial therapy delays relapse when medication is ceased).