To the Editor: In the introduction to their article, Rachel Yehuda, Ph.D., and colleagues (1) wrongly concluded from Solomon et al.’s study (2) of Israeli soldiers who developed posttraumatic stress disorder (PTSD) as a result of combat-related stress that "that study provided…empirical demonstration of a greater vulnerability of offspring of Holocaust survivors to…stressful events." This conclusion is not supported by Solomon et al.’s data. Solomon et al. may only have demonstrated that some of them were more vulnerable to PTSD. They did find statistically significant differences between their index and control groups in the number of symptoms reported. Inspection of their findings, however, suggests that there was considerable overlap between the groups. Furthermore, the mean frequency of any of the five symptoms for which data are reported is less than one per participant, raising some question about the clinical significance of the findings. Finally, because the study was based on questionnaire self-reports, the results may represent nothing more than differences in proneness of the respective groups to report symptoms and not a difference in vulnerability to PTSD.