Concerning the interaction between gender and diagnosis, we reanalyzed our data as suggested by Good and colleagues. Our findings do not support their contention that "sex differences in olfactory function in schizophrenia are age related." While we observed main effects of diagnosis (F=83.04, df=1, 70, p<0.0001), age (F=55.78, df=1, 79, p<0.0001), and a diagnosis-by-age interaction (F=43.43, df=1, 70, p<0.0001), there was no evidence for a main gender effect (F=1.23, df=1, 70, p=0.27), a gender-by-diagnosis interaction (F=1.79, df=1, 70, p=0.19), or an age-by-gender-by-diagnosis interaction (F=0.01, df=1, 70, p=0.93). Moreover, there is little evidence in the literature to support such a statement. Contrary to their own assertion that "female patients become impaired only postmenopausally," Kopala et al. R4815510CEBCEBII reported significant olfactory deficits in premenopausal schizophrenic women. Of the nine published studies that have included both male and female patients, only one R4815510CEBCEEFBobserved a significant gender-by-diagnosis interaction. The four others reporting sex differences employed less stringent statistical models and/or questionable contrasts (e.g. schizophrenic men versus a pooled group of schizophrenic women, healthy men, and healthy women).