Depressed elderly patients may indeed be less likely than younger patients to complain of low mood. We, in fact, recommended a two-item screening approach (assessing loss of interest as well as depressed mood), since it provides complete coverage of the core criterion symptoms of depression. The same logic is incorporated into most structured interviews, which allow skipping the remaining symptoms if depressed mood and loss of interest are both absent. In our study, however, addition of the loss-of-interest item did not actually improve diagnostic accuracy over the single-item approach. The accuracy of single-item screening in identifying depressive disorders in older adults has also been reported by other investigators (R1557294D).