Seventeen male outpatients with premature ejaculation were randomly
assigned to treatment with paroxetine (N = 8) or placebo (N = 9). After a
first week dose of 20 mg/day, the paroxetine regimen was increased to 40
mg/day for 5 weeks. Patients and their female partners were interviewed
separately. Patients treated with paroxetine had significantly greater
clinical improvement than the patients given placebo.