Eleven patients with tardive dyskinesia were treated in a double-blind
study of vitamin E or placebo for 12 weeks. Abnormal Involuntary Movement
Scale (AIMS) ratings were performed before and after treatment. Patients
receiving vitamin E showed a significant reduction in their AIMS scale
score, but patients receiving placebo showed no significant change. Vitamin
E had a helpful effect even for patients whose tardive dyskinesia was mild
and long-term.
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