The authors examined continued neuroleptic exposure following inpatient
treatment of mania with neuroleptics and lithium through structured chart
review of 40 consecutive patients. At discharge, patients were receiving a
mean of 793 mg/day (SD = 695) chlorpromazine equivalents; 6 months later
they were receiving a mean of 634 mg/day (SD = 684). This decrease was
statistically significant, but the patients' ongoing neuroleptic exposure
remained substantial.
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