Diabetes mellitus has been identified as a possible risk factor for
tardive dyskinesia. The authors examined 160 elderly individuals who were
beginning neuroleptic treatment; 24 had diabetes and 136 did not. After 43
weeks of neuroleptic exposure, the cumulative incidence rates of tardive
dyskinesia were 54.1% (SE = 5.6%) for the diabetics and 25.6% (SE = 16.1%)
for the nondiabetics.