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Hyperventilation-induced cerebral ischemia in panic disorder and effect of nimodipine
Am J Psychiatry 1992;149:1589-1591.
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Abstract

Basilar artery blood flow was measured by transcranial Doppler ultrasonography before and during hyperventilation in nine patients with panic disorder and nine normal comparison subjects. The hyperventilation-induced decrease in basilar artery blood flow was significantly greater in patients with panic attacks than in comparison subjects. Two patients with decreases in basilar flow greater than 80% were successfully treated with nimodipine, a centrally active calcium channel blocker.

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Hyperventilation-induced cerebral ischemia in panic disorder. Am J Psychiatry 1993;150(10):1567; author reply 1567-8.
Hyperventilation-induced cerebral ischemia in panic disorder. Am J Psychiatry 1993;150(10):1567; author reply 1567-8.