OBJECTIVE: Only scanty information on the prevalence of tardive
dyskinesia in Chinese patients has been available. This study was
undertaken to examine the prevalence of tardive dyskinesia, tardive
dystonia, and respiratory dyskinesia in Chinese psychiatric patients in
Hong Kong. METHOD: All inpatients of a mental hospital in Hong Kong, except
those in the admission and children's wards, were surveyed with the
Abnormal Involuntary Movement Scale, and standard research criteria were
used to establish the diagnosis of tardive dyskinesia. In addition,
patients were screened for tardive dystonia, according to published
criteria, and for respiratory dyskinesia by physical examination and
laboratory tests. RESULTS: Among the 917 patients surveyed, the prevalence
rates were 9.3% for tardive dyskinesia, 0.4% for tardive dystonia, and 1.2%
for respiratory dyskinesia. With multivariate analysis, greater age and a
lower current dose of antipsychotic, but not the presence of mood disorder,
were factors found to be significantly associated with tardive dyskinesia.
CONCLUSIONS: The prevalence rates were much lower than those found in
Western studies. This may indicate that there is an ethnic difference in
the prevalence of these conditions. Prospective cross-cultural studies are
necessary to explore this possibility.
Abstract Teaser