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The American Journal of Psychiatry, VOL. 149, No. 7

REGULAR ARTICLES | July 01, 1992

Replication of action of cholecystokinin tetrapeptide in panic disorder: clinical and behavioral findings

Am J Psychiatry 1992;149:962-964.

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Abstract

Eleven patients with panic disorder were challenged with cholecystokinin tetrapeptide (CCK-4) on two occasions. The effects of CCK-4 were consistent except symptom onset was more rapid with the second injection. Demonstrating that the effects of CCK-4 are reproducible in panic patients opens the doors for studies of the effects of drug treatment on CCK-4-induced panic.

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