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The American Journal of Psychiatry, VOL. 149, No. 5

REGULAR ARTICLES | May 01, 1992

Weight gain among schizophrenic patients treated with clozapine

Am J Psychiatry 1992;149:689-690.

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Abstract

A retrospective chart review was used to assess weight changes in 36 chronic schizophrenic inpatients who were treated with clozapine after being treated with standard neuroleptics. The average weight gain during 6 months of clozapine treatment was 16.9 lb; 75.0% of the patients gained at least 10 lb. The results confirm previous findings of clozapine-associated weight gain.

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