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The American Journal of Psychiatry, VOL. 148, No. 9

REGULAR ARTICLES | September 01, 1991

Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: a SPECT study

Am J Psychiatry 1991;148:1240-1242.

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Abstract

Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.

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