The recent and dramatic expansion in studies about borderline and
depressive disorders is reviewed with respect to the implications about
their interface. Revisiting this subject 6 years after an earlier review
reveals that intervening research has altered the conclusions that should
be drawn. Growing evidence from family history, comorbidity, phenomenology,
psychopharmacology, biological markers, and a new domain, pathogenesis,
indicates that a surprisingly weak and nonspecific relationship exists
between these disorders. Implications are drawn with respect to
classification, therapeutics, and defining the borderline construct.
Abstract Teaser