The authors used a double-blind crossover design to observe the effect
of transdermally administered nicotine on the smoking behavior of 13
psychiatric patients who were not trying to stop smoking. The patients
smoked significantly fewer cigarettes while receiving nicotine than while
receiving placebo. These data suggest that transdermally administered
nicotine can be a useful adjunct in treating nicotine- addicted psychiatric
patients in a non-smoking environment.