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The American Journal of Psychiatry, VOL. 147, No. 4

REGULAR ARTICLES | April 01, 1990

Effect of imipramine on depression and immune status in a sample of men with HIV infection

Am J Psychiatry 1990;147:495-497.

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Abstract

Eleven men with major depression and human immunodeficiency virus (HIV) infection underwent an open trial of imipramine. Eight of nine (89%) who completed 12 weeks responded. The mean decline in T4 cells from baseline was 100 at week 12 and 16 at week 26. No major exacerbations of HIV infection occurred.

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