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Treatment of Alzheimer's disease with short- and long-term oral THA and lecithin: a double-blind study

Published Online:https://doi.org/10.1176/ajp.147.2.239

Ten Alzheimer's disease patients underwent a trial of oral tetrahydroaminoacridine (THA) and lecithin. After 3 inpatient weeks there was no clear therapeutic effect. Three of six patients able to continue in long-term treatment showed measurable cognitive improvement, but only one displayed clinically obvious improvement.

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