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Subcortical hyperintensity on magnetic resonance imaging: a comparison of normal and depressed elderly subjects

Published Online:https://doi.org/10.1176/ajp.147.2.187

Subcortical hyperintensity on T2-weighted brain magnetic resonance imaging was significantly more common and more severe in elderly depressed patients referred for ECT than in a matched control group of normal elderly subjects. The potential clinical and research implications of these findings are discussed.

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