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Increase in desipramine serum levels associated with methadone treatment
Am J Psychiatry 1989;146:1611-1613.
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Abstract

Five men in a methadone treatment program who were also receiving desipramine had significantly higher desipramine serum levels when taking both drugs than when taking the antidepressant alone. Monitoring of desipramine serum levels may be useful with such patients.

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