The authors assessed life events during the 12 months before the onset
of panic disorder in 64 patients. Compared with a control group of 78
healthy subjects, patients with panic disorder had higher scores however
life events were assessed, i.e., number of events, weighted normative
scores, contextual scores, and number of subjects with major events.
Independent life events (those beyond the subject's control) were also more
numerous and more severe among the patients. The larger number of events
experienced by the patients was due to the more frequent occurrence of life
stress in the month before the onset of panic disorder. Loss events had the
strongest relationship to panic disorder.