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The American Journal of Psychiatry, VOL. 145, No. 10

REGULAR ARTICLES | October 01, 1988

Possible synergism between fluoxetine and lithium in refractory depression

Am J Psychiatry 1988;145:1292-1294.

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Abstract

Five depressed patients who had shown no improvement with trials of antidepressants from several chemical families, including fluoxetine, responded when lithium was given in conjunction with fluoxetine. Lithium augmentation of fluoxetine may represent a useful strategy in refractory depression.

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