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The American Journal of Psychiatry, VOL. 145, No. 7

REGULAR ARTICLES | July 01, 1988

Exacerbation of psychosis after discontinuation of carbamazepine treatment

Am J Psychiatry 1988;145:878-879.

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Abstract

Carbamazepine alone or carbamazepine plus neuroleptic was administered to 20 chronic schizophrenic patients. Upon abrupt discontinuation two of the 20 patients had exacerbations of their psychoses characterized by paranoia, hostility, and agitation. The authors discuss the possibility of a carbamazepine withdrawal syndrome.

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