Previous reports have noted an increased prevalence of obsessive-
compulsive symptoms in patients with panic disorder. The authors found a
prevalence of obsessive-compulsive symptoms in 19 (27%) of 70 patients with
panic disorder. Compared to a subgroup of 25 patients with classic features
of panic disorder and no obsessive-compulsive symptoms, the subgroup with
obsessive-compulsive symptoms had an earlier onset of illness, were more
likely to have personal and family histories of major depression and
substance abuse, and showed a poorer outcome after treatment.