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Relationship between physical anomalies and age at onset of schizophrenia

Published Online:https://doi.org/10.1176/ajp.144.5.666

Among 50 schizophrenic patients grouped by age at onset, the group with onset at or before age 18 had significantly more subjects with minor physical anomalies. These findings suggest that early-onset schizophrenia is associated with a more compromised CNS.

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