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The American Journal of Psychiatry, VOL. 143, No. 11

REGULAR ARTICLES | November 01, 1986

Withdrawal syndrome with gradual tapering of alprazolam

Am J Psychiatry 1986;143:1464-1466.

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Abstract

The clinical and biological correlates of gradual alprazolam withdrawal were investigated in 10 patients in a double-blind, placebo-controlled trial. During gradual alprazolam withdrawal, anxiety and plasma cortisol levels were higher than during a postwithdrawal medication- free period.

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