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Reduced TSH and prolactin responses to TRH in patients with panic disorder

Published Online:https://doi.org/10.1176/ajp.143.4.503

The authors studied the TSH and prolactin responses to a standard 500- micrograms thyrotropin-releasing hormone (TRH) stimulation test in 12 patients with panic disorder and 10 control subjects. As a group, panic disorder patients had lower mean TSH and prolactin responses, and female patients accounted for the lower prolactin response. The clinical and theoretical implications of these findings are discussed.

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