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The American Journal of Psychiatry, VOL. 143, No. 1

REGULAR ARTICLES | January 01, 1986

Combination alprazolam-neuroleptic treatment of the positive and negative symptoms of schizophrenia

Am J Psychiatry 1986;143:85-87.

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Abstract

Alprazolam, when added under double-blind conditions to a stable neuroleptic regimen in two patients with schizophrenia, resulted in clinically apparent improvement in positive and negative schizophrenic symptoms. Both patients showed significant worsening of symptoms following reduction or discontinuation of alprazolam.

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