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Depression after treatment with thiazide diuretics for hypertension

Published Online:https://doi.org/10.1176/ajp.142.9.1101

The authors reports eight cases of depression induced by thiazide diuretics prescribed for hypertension and discusses possible mechanisms behind this action. The side effects of thiazide diuretics may be overlooked when they are used with other hypertensives known to cause depression.

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