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Serial ECG measurements at controlled plasma levels of nortriptyline in depressed children

Published Online:https://doi.org/10.1176/ajp.142.9.1095

The authors investigated ECG measurements in 21 children with major depressive disorder treated with nortriptyline at plasma levels of 50- 100 ng/ml. P-R and QRS intervals and heart rate measured at baseline and once a week during treatment remained within guidelines.

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